【主持的科研项目】
1. 2024上海市东方英才计划青年项目，在研，主持。
2. 国家自然科学基金面上项目，82171657，G蛋白偶联雌激素受体驱动cGAS-STING通路促进复发性自然流产发生的机制研究，2022/01-2025/12，54万元，在研，主持。
3. 国家自然科学基金面上项目，81971384，蜕膜巨噬细胞中GPR133基因表达异常在复发性流产发生中的作用及机制研究，2020/01-2023/12，55万元，结题，主持。
4. 国家自然科学基金青年项目，81501270，赖氨酰氧化酶在子痫前期发生发展中的作用及其机制研究，2016/01-2018/12，18万元，结题，主持。
5. 上海市动物专项，22140903400，基于Gls1基因敲除的子宫内膜蜕膜化不良的动物模型构建，2022/03-2025/03，20万元，结题，主持。
6. 国家重点研发计划，基于早产发生机制的精准临床综合防控策略研究，2022/12-2025/11，2550万元，在研，课题骨干。
7. 上海市第一妇婴保健院院级基础研究专项面上项目，2025A08，磷脂酰胆碱PEMT合成途径调控子宫内膜蜕膜化的机制研究，2025/11至2026/10，5 万元，在研，主持。
【代表性论文】
1. Linchen Tang#, Xiang-Hong Xu#*(并列第一、共同通讯), Sha Xu, Zeying Liu, Qizhi He, Wenxuan Li, Jiaxue Sun, Wen Shuai, Jingwen Mao, Jian-Yuan Zhao, Liping Jin*. Dysregulated Gln-Glu-α-ketoglutarate axis impairs maternal decidualization and increases the risk of recurrent spontaneous miscarriage. Cell Rep Med. 2023 May 16;4(5):101026.
2. Hao F#, Tang LC#, Sun JX, Li WX, Zhao Y, Xu XH*(共同通讯), Jin LP*. Decreased nitric oxide content mediated by asymmetrical dimethylarginine and protein L-arginine methyltransferase 3 in macrophages induces trophoblast apoptosis: a potential cause of recurrent miscarriage. Hum Reprod. 2021, 36(12):3049-3061.
3. Haoyu Yang#, Cancan Wang#, Wenxuan Li#, Xin Su, Mengyuan Li, Qian Li, Xiang-Hong Xu*(共同通讯), Liping Jin*. Selection and validation of reference genes for gene expression studies of decidualization based on RNA sequencing. Reproductive Biology. 2025, 25(2):101023.
4. Linchen Tang#, Zhilong Wang#, Xianghong Xu#(并列第一), Yawei Yuan, Fan Hao, An Chen, Shengnan Wu, Wenxuan Li, Yanqiang Han, Jiaxue Sun, Kehao Tao, Zeying Liu, Zhiyun Wei, Jinjin Li, Liping Jin. Interpretable learning predicts miscarriage using pre-pregnancy serum metabolites. The Innovation Medicine 2(3): 100093, September 19, 2024.
5. Jia-Xue Sun, Yongli Yao, Wen-Xuan Li, Xin Su, Haoyu Yang, Zhouping Lu, Chenfei Liu, Xiang-Hong Xu*(共同通讯), Liping Jin*. Upregulation of GPR133 expression impaired the phagocytosis of macrophages in recurrent spontaneous miscarriage. Epigenetics. 2024;19(1):2337087.
6. Yan Zhao, Yongbo Zhao, Jianlong Zhu, Lei Lei, Baohua Zhang, Xianghong Xu*(共同通讯), Liping Jin*. Association of inactivated COVID-19 vaccination with maternal coagulation function in early pregnancy. J Med Virol. 2023 Aug;95(8):e29051.
7. Sun JX, Xu XH*(共同通讯), Jin LP*. Effects of Metabolism on Macrophage Polarization Under Different Disease Backgrounds. Front Immunol. 2022, 13:880286.
8. Li WX, Xu XH*(共同通讯), Jin LP*. Regulation of the innate immune cells during pregnancy: An immune checkpoint perspective. J Cell Mol Med. 2021, 25(22):10362-10375.
9. Xu XH#, Tang LC#, Hao F, Jin LP*. Upregulation of miR-29a suppressed the migration and invasion of trophoblasts by directly targeting LOXL2 in preeclampsia. Journal of hypertension. 2021, 39(8):1642-1651.
10. Tang LC, Xu XH*(共同通讯), Jin LP*. Molecular characteristics and possible functions of innate lymphoid cells in the uterus and gut. Cytokine Growth Factor Rev. 2020, 52:15-24.
11. Yao Y#, Hao F, Tang LC, Xu XH*(共同通讯), Jin LP*. Downregulation of HDAC8 expression decreases CD163 levels and promotes the apoptosis of macrophages by activating the ERK signaling pathway in recurrent spontaneous miscarriage. Mol Hum Reprod. 2020, 26(7):521-531.
12. Xu XH#, Jia Y, Zhou X, Xie D, Huang X, Jia L, Zhou Q, Zheng Q, Zhou X, Wang K*, Jin LP*. Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating TGF-β/collagen pathway in preeclampsia. Exp Mol Med. 2019, 51 (2): 20.
13. Yao Y, Xu XH*(共同通讯), Jin LP*. Macrophage Polarization in Physiological and Pathological Pregnancy. Front Immunol. 2019, 10:792.
14. Fan DX#, Zhou WJ#, Jin LP, Li MQ, Xu XH*(共同通讯), Xu CJ*. Trophoblast-Derived CXCL16 Decreased Granzyme B Production of Decidual γδ T Cells and Promoted Bcl-xL Expression of Trophoblasts. Reprod Sci. 2019, 26(4):532-542.
15. Xu XH#, Bao Y#, Wang X, Yan F, Guo S, Ma Y, Xu D, Jin L, Xu J*, Wang J*. Hypoxic-stabilized EPAS1 proteins transactivate DNMT1 and cause promoter hypermethylation and transcription inhibition of EPAS1 in non-small cell lung cancer. FASEB J. 2018, 32(12): 6694-6705.
