近5年主持课题：
国家重点研发计划，2022YFC2704700，建立我国胎儿生长曲线和胎儿生长受限干预体系的全链条研究，2022.12-2025.11，2200万元，项目及课题3负责人（PI: The National Key Research and Development Program of China (Granted number 2022YFC2704700), Establishment of Chinese fetal growth curve and whole-chain research on intervention system of fetal growth restriction, RMB 22 million, Dec 2022 to Nov. 2025.）
上海市2021年度“科技创新行动计划”医学创新研究专项，21Y11907500，胎儿生长受限精准产前遗传诊断及干预策略研究，30万，2021.10 -2024.9. （PI: "Science and Technology Innovation Plan" of Shanghai Medical Innovation Research Projects, 2021 (Granted number: 21Y11907500), Research on accurate prenatal genetic diagnosis and intervention strategy for fetal growth restriction, RMB 300 thousand, Oct. 2021 to Sep.2024.）
上海申康医院发展中心临床三年行动计划资助， SHDC2020CR6028-005，儿童罕见病队列数据库及共享平台建设与应用，19.5万元，2020.12.1-2022.9.30（PI: Three-year Clinical Action Plan of Shanghai Shen-kang Hospital Developmental Center, (Granted number: SHDC2020CR6028-005), Construction and application of cohort, database and sharing platform for Rare diseases in children, RMB 195 thousand, Dec. 2020 to Sep. 2022.）
国家自然科学基金面上项目, 82071656, TRIM31在胎盘发育不良致胎儿生长受限中的作用及其调控机制研究，2021.1-2024.12，52万元，主持.（PI: National Natural Science Foundation Project (Granted number: 82071656), The role and mechanism of TRIM31 dysfunction in pathogenesis fetal growth restriction, 520 thousand, Jan. 2021 to Dec.2024.）
国家重点研发计划，2018YFC1002900，，2018/07-2020/12, 1247万元，结题，项目骨干及子课题负责人（“重大胎儿疾病宫内诊断和干预相关因素初探”，经费80万元）（Co-Applicant: The National Key Research and Development Program of China (Granted number: 2018YFC1002900), Research and development of new technologies for intrauterine diagnosis and treatment of major fetal diseases, RMB 12.47 million, Jul. 2018 to Dec. 2020.）
上海市申康新兴前沿技术，SHDC12016117，双胎妊娠胎儿染色体及结构异常的产前筛查、诊断及宫内干预，2017/01-2019/12（PI: Project on Emerging Frontier technology of Shanghai Shen-kang Hospital Developmental Center (Granted number: SHDC12016117), Prenatal screening, diagnosis and intrauterine intervention of fetal chromosome and structure abnormalities in twin pregnancies, RMB 1.2 million, Sep. 2016 to Sep. 2019.）
上海市科学技术委员会，16411963100，双胎妊娠孕早期早发型子痫前期的风险预测研究项目（课题）编号16411963100，2016-2019年（PI: Shanghai Municipal Science and Technology Commission (Granted number: 16411963100), Prediction of early-onset preeclampsia in twin pregnancies, RMB 200 thousand, Jun. 2016 to Jun. 2019.）
上海市卫生和计划生育委员会，201540195，孕早中期母体血清Leptin水平预测胎盘介导的胎儿生长受限的研究，2016/01-2019/01（PI: Shanghai Health and Family Planning Commission (Granted number: 201540195), Prediction of placenta mediated fetal growth restriction using second-trimester maternal serum Leptin levels, RMB 50 thousand, Jan. 2016 to Jan. 2019.）
上海市科学技术委员会，134119a4400，双胎妊娠特殊并发症孕早期风险的预测研究，2013/06-2016/06，20万，主持（PI: Shanghai Municipal Science and Technology Commission (Granted number: 134119a4400), Special twin pregnancy complication of early pregnancy risk prediction research, RMB 200 thousand, Jun. 2013 to Jun. 2016.）
上海市自然科学基金，12ZR1423900，胎盘功能不良介导的尿道下裂发生的分子机制探讨，2012/07-2015/06，10万元，课题负责人（PI: Shanghai Natural Science Foundation (Granted number: 12ZR1423900), Investigation on the molecular mechanism of placental dysfunction mediated hypospadias, RMB 100 thousand, RMB 100 thousand, Jul. 2012 to Jun. 2015.）
上海市人口和计划生育委员会，2011JG10，胎儿宫内生长受限的差异基因表达谱研究，2011-2013年，课题负责人（PI: Shanghai Population and Family Planning Commission (Granted number: 2011JG10), Research on differences in gene expression profile of fetal growth restriction, RMB 50 thousand, 2011-2013.）
上海市申康管理课题， SHDC201162，胎儿医学基础上构建的出生缺陷管理和诊治模式，2010-2012年 课题责任人（Management Project of Shanghai Shen-Kang Hospital Developmental Center (Granted number: SHDC201162), Construction of management, diagnosis and treatment model for birth defects on the basis of Fetal medicine, 2010-2012.）
主要执笔指南（main author in guidelines）
中华医学会围产医学分会胎儿医学学组, 中华医学会妇产科学分会产科学组. 双胎妊娠临床处理指南(2020年更新)（Guideline for management of twin pregnancy (2020 update)）[J]. 中华围产医学杂志, 2020, 23(08):505-516.
中华医学会围产医学分会胎儿医学学组，中华医学会妇产科学分会产科学组，孙路明，胡娅莉，漆洪波. 胎儿生长受限专家共识（2019 版）（Expert consensus on fetal growth restriction）. 中华围产医学杂志，2019, 22 (6): 361-380.
中华医学会围产医学分会胎儿医学学组, 中华医学会妇产科分会产科学组. 胎儿非免疫性水肿临床指南（Clinical Guidelines for nonimmune hydrops fetalis）.中华围产医学杂志, 2017,20(11):769-775.
双胎妊娠临床处理指南(第一部分)——双胎妊娠的孕期监护及处理（Guidelines for clinical management of twins (Part 1): In-terpretation of twin pregnancy care and management）. 中华妇产科杂志，2015
双胎妊娠临床处理指南(第二部分)——双胎妊娠并发症的诊治（Guidelines for clini-cal management of twins (Part 2): Diagnosis and treatment of twin pregnancy complica-tions）. 中华妇产科杂志，2015
近5年SCI论文（#为共同第一作者，*为通讯作者）
ZHU Dan, WEI Xing, ZHOU Xin-yao, DENG Lin-bei, XIONG Shi-yi, CHEN Jian-ping, CHEN Guang-quan, ZOU Gang, SUN Lu-ming. Chromosomal abnormalities in recurrent pregnancy loss and its association with clinical characteristics. Journal of Assisted Reproduction and Genetics, accepted
Jiang H, Li L, Zhu D, Zhou X, Yu Y, Zhou Q, Sun L. A Review of Nanotechnology for Treating Dysfunctional Placenta. Front Bioeng Biotechnol. 2022 Mar 24;10:845779. doi: 10.3389/fbioe.2022.845779. PMID: 35402416; PMCID: PMC8987505.
Wei X, Yang Y, Zhou J, Zhou X, Xiong S, Chen J, Zhou F, Zou G, Sun L. An Investigation of the Etiologies of Non-Immune Hydrops Fetalis in the Era of Next-Generation Sequence-A Single Center Experience. Genes (Basel). 2022 Nov 28;13(12):2231. doi: 10.3390/genes13122231. PMID: 36553497; PMCID: PMC9778190.
Hu X, Xiong S, Zhou X, Sun L. Generation of a human induced pluripotent stem cell line FMUPDCi001-A from a patient with mental retardation, autosomal recessive 36 (MRT36) carrying the variants c.219dupA and c.587C > T in ADAT3. Stem Cell Res. 2022 May;61:102777. doi: 10.1016/j.scr.2022.102777. Epub 2022 Apr 4. PMID: 35405382.
Kong L, Li S, Zhao Z, Feng J, Liu L, Tang W, Zhang H, Wu D, Sun L*, Kong X*. Noninvasive prenatal testing of Duchenne muscular dystrophy in a twin gestation. Prenat Diagn. 2022 Apr;42(4):518-523. doi: 10.1002/pd.6124. Epub 2022 Mar 7.PMID: 35220584
Chen G, Xiong S, Jing Q, van Gestel CAM, van Straalen NM, Roelofs D, Sun L*, Qiu H*. Maternal exposure to polystyrene nanoparticles retarded fetal growth and triggered metabolic disorders of placenta and fetus in mice. Sci Total Environ. 2022 Sep 13;854:158666. doi: 10.1016/j.scitotenv.2022.158666. Epub ahead of print. PMID: 36108837.
Sun K, Yao Y, Yun L, Zhang C, Xie J, Qian X, Tang Q, Sun L*. Application of machine learning for ancestry inference using multi-InDel markers. Forensic Sci Int Genet. 2022 Jul;59:102702. doi: 10.1016/j.fsigen.2022.102702. Epub 2022 Mar 30. PMID: 35378426.
Xing Y, Zhang Y, Chen J, Wu F, Yuan M, Zou G, Yang Y, Zhou F, Zhou J, Sun L*. Prenatal diagnosis for fetuses with isolated and non-isolated congenital heart defects using chromosomal microarray and exome sequencing. Prenat Diagn. 2022 Jun;42(7):873-880. doi: 10.1002/pd.6168. Epub 2022 May 24. PMID: 35584285.
Deng L, Liu Y, Yuan M, Meng M, Yang Y, Sun L*. Prenatal diagnosis and outcome of fetal hyperechogenic kidneys in the era of antenatal next-generation sequencing. Clin Chim Acta. 2022 Mar 1;528:16-28. doi: 10.1016/j.cca.2022.01.012. Epub 2022 Jan 20. PMID: 35065907.
Wei X, Zhou X, Zhou J, Zou G, Yang Y, Zhou F, Xiong S, Chen J, Sun L*. The value of exome sequencing in thoracoamniotic shunt for severe pleural effusion with fetal hydrops: a retrospective clinical study. Fetal Diagn Ther. 2022 Feb 9. doi: 10.1159/000521212. Epub ahead of print. PMID: 35139508.
Cai L, Yang Y, Zou G, Zhang Y, Wu F, Yuan M, Zhou Y, Chen J, Sun L*. Pregnancy Loss After Amniocentesis with Double-Needle Insertions in Twin Pregnancies. Twin Res Hum Genet. 2022 Mar 7:1-6. doi: 10.1017/thg.2022.1. Epub ahead of print. PMID: 35249587.
Chen G, Xiong S, Zou G, Wu F, Qu X, Alawbathani S, Sun L. A 6.3 Mb maternally derived microduplication of 20p13p12.2 in a fetus with Brachydactyly type D and related literature review. Mol Cytogenet. 2022 Feb 28;15(1):6. doi: 10.1186/s13039-022-00584-3. PMID: 35227291; PMCID: PMC8887085.
Jia Zhou#, Ziying Yang#, Jun Sun#, Lipei Liu, Xinyao Zhou, Fengxia Liu, Ya Xing, Shuge Cui, ShiyiXiong, Xiaoyu Liu, Yingjun Yang, Xiuxiu Wei, Gang Zou, Zhonghua Wang, Xing Wei, Yaoshen Wang, Yun Zhang, Saiying Yan, Fengyu Wu1, Fanwei Zeng, Jian Wang, Tao Duan, ZhiyuPeng* and Luming Sun*(通讯). Whole Genome Sequencing in the Evaluation of Fetal Structural Anomalies: A Parallel Test with Chromosomal Microarray Plus Whole Exome Sequencing. Genes (Basel). 2021 Mar 6;12(3):376. doi: 10.3390/genes12030376. PMID: 33800913; PMCID: PMC7999180.
Jianping Chen, Jun Zhang, Yang Liu, Xing Wei, Yingjun Yang, Gang Zou, Yun Zhang, Tao Duan, Luming Sun*(通讯). Fetal growth standards for Chinese twin pregnancies.BMC Pregnancy Childbirth.2021 Jun 22;21(1):436.
Xinyao Zhou, Jia Zhou, Xing Wei, Ruen Yao, Yingjun Yang, Linbei Deng, Gang Zou, Xietong Wang, YAPING YANG, Tao Duan, Jian Wang, Luming Sun*(通讯). Value of exome sequencing in diagnosis and management of recurrent nonimmune hydrops fetalis: A retrospective analysis. Frontiers in Genetics, 2021 Apr 9;12:616392.
Jianping Chen, Depeng Zhao, Yang Liu , Jia Zhou , Gang Zou, Yun Zhang , Ming Guo , Tao Duan , Tim Van Mieghem , Luming Sun*(通讯). Screening for Preeclampsia in Low-Risk Twin Pregnancies at Early Gestation. Acta Obstet Gynecol Scand. 2020 Apr 30. doi: 10.1111/aogs.13890. Online ahead of print.
Meizhen Yuan#, Linbei Deng#, Yingjun Yang, Luming Sun*(通讯).Intrauterine phenotype features of fetuses withWilliams–Beuren syndrome and literature review. Ann Hum Genet. 2019;1–8. Accepted: 23 September 2019 DOI: 10.1111/ahg.12360 IF= 1.319
Sun L*, Zou G, Yang Y, Zhou F, Tao D*. Risk factors for fetal death after radiofrequency ablation for complicated monochorionic twin pregnancies. Prenat Diagn. 2018 Jun;38(7):499-503.
Deng L, Cheung SW, Schmitt ES, Xiong S, Yuan M, Chen Z, Chen L, Sun L*(通讯). Targeted gene panel sequencing prenatally detects two novel mutations of DYNC2H1 in a fetus with increased biparietal diameter and polyhydramnios. Birth Defects Res. 2018 Mar 1;110(4):364-371.
Zhou X, Chandler N, Deng L, Zhou J, Yuan M, Sun L*(通讯). Prenatal diagnosis of skeletal dysplasias using a targeted skeletal gene panel. Prenat Diagn. 2018 Aug;38(9):692-699.
Xing Y, Holder JL Jr, Liu Y, Yuan M, Sun Q, Qu X, Deng L, Zhou J, Yang Y, Guo M, Cheung SW, Sun L*(通讯). Prenatal diagnosis of Wolf-Hirschhorn syndrome: from ultrasound findings, diagnostic technology to genetic counseling. Arch Gynecol Obstet. 2018 Aug;298(2):289-295.
Sun L*, Zou G, Zhou F, Yang Y, Oepkes D, Duan T. Outcome of dichorionic triamniotic triplet: the experience from an emerging fetal therapy center. J Matern Fetal Neonatal Med. 2018 Dec;31(23):3075-3079.
